Western Governors University (WGU) NURS5204 D027 Advanced Pathopharmacological Foundations Practice Exam

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Which condition is Prazosin commonly used for off-label?

Benign prostatic hyperplasia (BPH)

Prazosin is commonly used off-label for treating anxiety disorders, particularly post-traumatic stress disorder (PTSD). While it is well-known for its primary indications, such as hypertension and benign prostatic hyperplasia (BPH), its effectiveness in alleviating nightmares and other symptoms associated with PTSD makes it a valuable off-label option in psychiatric settings.

Prazosin works by antagonizing alpha-1 adrenergic receptors, which helps to reduce sympathetic outflow and, subsequently, the autonomic symptoms associated with anxiety. By blocking these receptors, it can help patients who experience severe nighttime anxiety symptoms, leading to improved sleep quality and reduced anxiety during the day. This off-label use showcases the broader utility of Prazosin beyond its recognized applications, highlighting the importance of understanding its pharmacological effects in various clinical scenarios.

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Hypertension

Type 2 diabetes

Anxiety disorders

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